Medical therapy for Acanthamoeba Infection is not well established. Early diagnosis and treatment are paramount for improving outcome.Successful treatment of Keratitis consists of early diagnosis and aggressive surgical and medical therapies.Medical treatment consists of topical Antimicrobial Agents, which can achieve high concentrations at the site of the infection.
These topical Antimicrobials are administered every hour immediately after the first several days of therapy. These agents are then continued hourly during waking hours for 3 days. The frequency is then reduced to every 3 hours. Two weeks may be required before a response is observed, and the total duration of therapy is a minimum of 3-4 weeks. Some advocate treating for 6-12 months. When therapy is discontinued, close observation is warranted to rule out recurrent disease.
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